Welcome to the Creek
We are a research and development company realizing the full potential of fungi in addressing the greatest medical challenges of our time.
Kapoose Creek Discovery
The World's Most Comprehensive Fungal Library
Kapoose Creek is building the world’s most complete fungal library by cataloging the diverse biology and chemistry that exists in unique and unexplored natural ecosystems. We systematically mine this expansive resource for undiscovered chemistry that will inspire new medicines and health products.
Kapoose Creek Development
A New Approach to Therapeutic Research
We are reinventing drug discovery to learn from nature on an unprecedented scale. We leverage world-leading science to probe the many medicinal properties of fungi and maximize the therapeutic potential of their chemistry.
An Ecosystem Ripe for Therapeutic Discovery
Our innovations begin in a land of uninterrupted evolution
Kapoose Creek, located on the northwest Pacific coast of Vancouver Island, was part of a rare ice-free corridor during the last ice age. As a result, this land has a rich ecosystem and unique mycological biodiversity.
Fungi is Medicine
Nearly a century ago, the discovery of Penicillin (derived from fungi), became the first mass-produced antibiotic, changing the course of medicine and human history alike.
We aim to make our own mark on the course of history.
5,000,000
Estimated number of fungal species on earth
>90%
Estimated percentage of fungal species that are still unknown and ripe for discovery
50
Estimated drug-like compounds in each species of fungi
320
Acres of Kapoose Creek lands, a rainforest rich in biodiversity and fungal activity
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There are zero roads leading to the pristine lands of Kapoose Creek – it’s only accessible via boat, plane, or helicopter
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We’ve built a state-of-the-art off-grid mycological research station in a temperate rainforest, enabling real-time evaluation of the unique chemistry only expressed by fungi in their natural environment
Laying the Groundwork for the Future of Myco-based Therapeutics
With over 100 million unique fungal compounds in the world, and hundreds of acres of remote forest to explore, we aim to discover the next generation of world-changing medicinal compounds
From the Underground Up
Our novel Discovery Platform screens rare and unique fungi for a wide variety of indications
Discovery Platform
Forage & Culture
Mycologists carefully search the KC forest for fungi, recording GPS coordinates and details on the morphology and environment of harvested samples. A sustainable quantity of the fungi and surrounding substrate are then collected for evaluation at the KC Research Station.
Value Created:
KC Fungal Collection & Genetics Library
Analyze & Profile
At the Kapoose Creek Research Station, we evaluate rare, unique fungi for medicinal potential. We are agnostic to therapeutic application, asking instead what medicines nature has designed using state-of-the-art machine-learning and drug discovery platforms.
Value Created:
KC Therapeutic Pipeline
Characterize & Synthesize
Top leads from our KC Therapeutic Pipeline are subject to characterization and biosynthesis, powered by advanced sequencing and synthetic biology capabilities.
Value Created:
KC Therapeutic Leads
Development Process
Concept Development
Leveraging decades of in-house formulation, design, and development experience, the KC Product Innovation Engine transforms natural medicines and newly discovered compounds into optimized human-centered therapeutics.
Value Created:
KC Formulation Tech
Analysis & Standardization
Dosage format, excipient selection, and packaging are carefully considered to ensure stability and a positive user experience, while defined manufacturing and quality protocols ensure scalability and compliance with applicable regulations.
Value Created:
KC Delivery Formats
Pre-Clinical & Clinical Trials
Kapoose Creek is actively developing a portfolio of evidence-based therapeutics. Given their history of use, these products enter the product innovation pipeline at a later stage with an expedited path to approval relative to a new chemical entity.
Value Created:
KC Therapeutics
Regulatory Pathways
Rx
Leads are subject to in-depth analysis and pre-clinical testing to gather data on mechanism of action, safety, pharmaco-kinetics, pharmaco-dynamics, and dosing profile, then move through the regulatory process to authorize use in full clinical trials. We pursue development and licensing partnerships with pharmaceutical and biotechnology firms in order to advance assets through Phase 2 trials and beyond.
OTC
Functional mushrooms used in traditional medicine have proven safe and effective through centuries of use. KC’s Discovery Platform looks deeper into these fungi, uncovering the chemistry behind their unique properties and health applications. Our discovery program establishes the evidence base to substantiate the health benefits of fungi, providing market differentiation and paths to novel health claims.
Clinically Tested, Scientifically Proven
Clinical Research efforts designed to validate fungi-derived therapeutics
Our trials are dedicated to proving the safety and efficacy of powerful fungi compounds, including psilocybin
Concentrating Our Efforts
Optimized Product Formats
Our patented delivery systems leverage proprietary extraction techniques to provide targeted doses of active compounds to affected areas of the body for maximum absorption and benefit.
A Team Effort
The myco revolution needs the right people to lead the way
We’ve assembled an interdisciplinary group of world-class scientists, seasoned business leaders, and pioneers from medicine and academia.
Meet the full team
Sam Feldman
Founder & Chairman
Dr. Eric Brown
Chief Executive Officer
Peter Crooks
Chief Innovation Officer
Jonathan Jackson
Chief Operating Officer
Victoria MacPhail
VP of Finance
Dr. Joe Gabriele
Chief Science Advisor
Jeremy Wright
Chief Financial Advisor
Dr. Michael Frankel
Chief Medical Advisor
A Network of Labs
Alliances that deepen our scientific capabilities
Our partnerships with academic institutions, including McMaster University and University of Victoria, amplify our resources with some of the world’s top scientists, state-of-the-art equipment, drug discovery platforms, robotic automation, artificial intelligence, natural product screening, and more.
